An isocratic high performance liquid chromatography (HPLC) assay for moxifloxacin, a new 8-methoxyquinolone
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چکیده
منابع مشابه
High-performance liquid chromatography (HPLC) assay for ribavirin and comparison of the HPLC assay with radioimmunoassay.
The use of high-performance liquid chromatography (HPLC) to measure ribavirin in serum and other biological fluids has been limited by endogenous interfering substances. We report an HPLC procedure based on the extraction of ribavirin from serum, plasma, or cerebrospinal fluid with a boronate affinity gel, which uses a 3-methylcytidine internal standard. This assay is sensitive (to 0.4 microM),...
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High-performance liquid chromatography (HPLC) is a refinement of traditional column chromatographic techniques. The speed of analysis and the resolution are increased with new column-packing materials and eluant pumped through the column at high pressure. The potential for achieving measurements of hormones in small volumes of plasma or urine is limited, both in normal and pathological situatio...
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Sir, Linezolid, a new oxazolidinone, has a unique mode of action.1 The antimicrobial agent has a wide spectrum of activity against Gram-positive organisms, including methicillinresistant Staphylococcus aureus,2,3 penicillin-resistant pnemococci3 and both vancomycin-resistant Enterococcus faecalis and Enterococcus faecium.3,4 Linezolid is available in oral and intravenous (iv) preparations and n...
متن کاملA Rapid Isocratic High Performance Liquid Chromatography (hplc-uv) Method for the Quantification of Ritonavir in Human Plasma
Objective: An accurate, simple, and rapid HPLC-UV based method for the quantitative determination of ritonavir (RTV) in human plasma is developed. Methods: The method involved deproteinization of the sample with 0.125N NaOH and methyl tertiary butyl ether and evaporated to dryness. The residue was reconstituted with mobile phase (20 mM Sodium Acetate and Acetonitrile–55:45 v/v). The analysis wa...
متن کاملA rapid, isocratic method for phospholipid separation by high-performance liquid chromatography.
A rapid, isocratic method for separating the most prevalent phospholipids by high-performance liquid chromatography is described. Baseline resolution of phosphatidylinositol, phosphatidylserine, phosphatidylethanolamine, phosphatidylcholine, lysophosphatidylcholine, and sphingomyelin is achieved in less than 40 min on a silica column. Lipids are injected in 10 microliter of chloroform-diethyl e...
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ژورنال
عنوان ژورنال: Journal of Antimicrobial Chemotherapy
سال: 1998
ISSN: 1460-2091
DOI: 10.1093/jac/42.2.278